[HTML][HTML] Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration
K Bartlette, AM Carreau, D Xie, Y Garcia-Reyes… - Metabolism open, 2021 - Elsevier
Abstract Introduction The Oral Minimal Model (OMM), a differential-equations based
mathematical model of glucose-insulin dynamics, utilizes data from a frequently sampled
oral glucose tolerance test (OGTT) to quantify insulin sensitivity (SI). OMM-based estimates
of SI can detect differences in insulin resistance (IR) across population groups and quantify
effects of clinical or behavioral interventions. These estimates of SI have been validated in
healthy adults using data from OGTTs with durations from 2 to 7 h. However, data …
mathematical model of glucose-insulin dynamics, utilizes data from a frequently sampled
oral glucose tolerance test (OGTT) to quantify insulin sensitivity (SI). OMM-based estimates
of SI can detect differences in insulin resistance (IR) across population groups and quantify
effects of clinical or behavioral interventions. These estimates of SI have been validated in
healthy adults using data from OGTTs with durations from 2 to 7 h. However, data …
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