Orientation-specific attachment of polymeric microtubes on cell surfaces

JB Gilbert, JS O'Brien, HS Suresh, RE Cohen… - 2013 - dspace.mit.edu
JB Gilbert, JS O'Brien, HS Suresh, RE Cohen, MF Rubner
2013dspace.mit.edu
Tubular particles presenting heterogeneous regions of chemistry on the tube-ends versus
the side are fabricated and are shown to control the particle orientation on the surface of live
lymphocytes. Controlling the orientation of anisotropic microparticles on cell surfaces is of
interest for biomedical applications and drug delivery in particular, since it can be used to
promote or resist particle internalization.
Tubular particles presenting heterogeneous regions of chemistry on the tube-ends versus the side are fabricated and are shown to control the particle orientation on the surface of live lymphocytes. Controlling the orientation of anisotropic microparticles on cell surfaces is of interest for biomedical applications and drug delivery in particular, since it can be used to promote or resist particle internalization.
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