[HTML][HTML] Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats
X Liu, K Chen, Y Zhuang, Y Huang, Y Sui… - Biomedicine & …, 2019 - Elsevier
X Liu, K Chen, Y Zhuang, Y Huang, Y Sui, Y Zhang, L Lv, G Zhang
Biomedicine & Pharmacotherapy, 2019•ElsevierHighlights•Paeoniflorin was first investigated to improve cardiac remodeling by modulating
MAPK pathway.•Cardiac remodeling was measured in different forms, including cardiac
hypertrophy and fibrosis.•High throughput sequencing were used to clarify the mechanism of
paeoniflorin.
MAPK pathway.•Cardiac remodeling was measured in different forms, including cardiac
hypertrophy and fibrosis.•High throughput sequencing were used to clarify the mechanism of
paeoniflorin.
Highlights
- Paeoniflorin was first investigated to improve cardiac remodeling by modulating MAPK pathway.
- Cardiac remodeling was measured in different forms, including cardiac hypertrophy and fibrosis.
- High throughput sequencing were used to clarify the mechanism of paeoniflorin.
Elsevier
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