Pathway to demonstrating clinical efficacy of microwave breast imaging: Qualitative and quantitative performance assessment

E Porter, D O'Loughlin - … , RF and Microwaves in Medicine and …, 2022 - ieeexplore.ieee.org
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine …, 2022ieeexplore.ieee.org
In the last five years alone, there has been an increasing number of operational microwave
breast imaging systems used in clinical trials, with increasingly large and diverse patient
populations. However, despite this increased activity and volume of clinical evidence
motivating research in the modality, large differences exist in how studies evaluate and
report their findings. In this work, the qualitative and quantitative metrics used to measure
both image quality and clinical effectiveness and efficacy are reviewed in detail. Image …
In the last five years alone, there has been an increasing number of operational microwave breast imaging systems used in clinical trials, with increasingly large and diverse patient populations. However, despite this increased activity and volume of clinical evidence motivating research in the modality, large differences exist in how studies evaluate and report their findings. In this work, the qualitative and quantitative metrics used to measure both image quality and clinical effectiveness and efficacy are reviewed in detail. Image quality, effectiveness and efficacy do not have precise or agreed definitions and the differences between these definitions are discussed in detail. Finally, based on these understandings, the current evidence for clinical acceptance of microwave breast imaging is reviewed, with an emphasis on gaps in the trial populations to date.
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