Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease

K Yamamoto, Y Ishizu, T Honda, T Ito, N Imai… - Scientific Reports, 2022 - nature.com
Sarcopenia is thought to be related to the microbiome, but not enough reports in chronic
liver disease (CLD) patients. In addition to the differences in microbiome, the role of the
microbiome in the gut is also important to be clarified because it has recently been shown
that the microbiome may produce branched-chain amino acids (BCAAs) in the body. In this
single-center study, sixty-nine CLD patients were divided by skeletal muscle mass index
(SMI) into low (L-SMI: n= 25) and normal (N-SMI: n= 44). Microbiome was analyzed from …

[引用][C] Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease. Sci Rep 12: 3674

K Yamamoto, Y Ishizu, T Honda - 2022
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