Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway

K Fu, M Chen, H Zheng, C Li, F Yang… - Translational …, 2021 - degruyter.com
Background Morbidity and mortality remain high for ischemic stroke victims, and at present
these patients lack effective neuroprotective agents, which improve the cure rate. In recent
years, studies have shown that pelargonidin has many biological actions. However, few
studies are available regarding the pelargonidin treatment of cerebral ischemia. Methods
The rat middle cerebral artery occlusion (MCAO) model was established to investigate the
neuroprotective effect of pelargonidin on cerebral ischemia/reperfusion injury. Reperfusion …

[引用][C] Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway. Transl Neurosci. 2021; 12: 20–31

K Fu, M Chen, H Zheng, C Li, F Yang, Q Niu
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