The purpose of this research is to investigate and measure the level of financial literacy and its variables in the growth of SMEs in Palembang, South Sumatra, Indonesia. This study explains how the level of understanding of small and medium enterprises in Palembang City in implementing the level of sharia financial literacy either directly or through the level of experience in the growth of SMEs in Palembang City. The research sample consisted of 380 SME players in Palembang city and related parties from 7470 objects of the population studied in the city of Palembang. In the study, a survey method based on quantitative data was utilized. The research data were collected through a quantitative survey and analyzed using IBM SPSS 25. The results of this study confirm the relationship between Islamic financial literacy, the experience of business actors, and the growth of SMEs. The results of the study have revealed that Islamic financial literacy increases the growth of SMEs in Palembang. The study also provides an alternative solution in the form of information for policy-makers in developing a growth strategy for SMEs in Palembang by strengthening Islamic financial literacy, especially for SME business actors who already have entrepreneurial experience.