Objective To summarize the available evidence about the perioperative management of
patients who are receiving long-term antiplatelet therapy and require elective
surgery/procedures. Methods This systematic review supports the development of the
American College of Chest Physicians guideline on the perioperative management of
antiplatelet therapy. A literature search of MEDLINE, EMBASE, Scopus and Cochrane
databases was conducted from each database's inception to July 16, 2020. Meta-analyses …

Worldwide, cardiovascular events represent the major cause of morbidity and mortality. A
key role in the pathogenesis of these events is played by platelets. Interventional
procedures, with placement of coronary and vascular stents, often represent the preferred
therapeutic strategy. Antiplatelet medications are considered first-line therapy in preventing
cardiovascular thrombotic events. A wide array of antiplatelet agents is available, each with
different pharmacological properties. When patients on antiplatelet agents present for …