Catuama is a marketed herbal product currently used as a tonic, especially for the
management of mental or physical fatigue. In the present study, we have shown
pharmacological and neurochemical evidence for antidepressant-like actions of the product
Catuama. Acute and chronic oral treatments with Catuama both resulted in a significant
reduction of the immobility time in two models of depression in mice, the forced swimming
and the tail suspension tests. Conversely, treatment with the same doses of Catuama did not …