Photodynamic inactivation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with Ru (II)-based type I/type II photosensitizers

Y Arenas, S Monro, G Shi, A Mandel… - Photodiagnosis and …, 2013 - Elsevier
Background The introduction of new disinfection and sterilization methods, such as
antimicrobial photodynamic therapy, is urgently needed for the healthcare industry, in
particular to address the pervasive problem of antibiotic resistance. This study evaluated the
efficacy and the mechanisms of photodynamic antimicrobial chemotherapy (PACT), also
known as photodynamic inactivation (PDI) of microorganisms, induced by novel Ru (II)-
based photosensitizers against Staphylococcus aureus and methicillin-resistant S. aureus …
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