Physiology and mRNA expression in rainbow trout (Oncorhynchus mykiss) after long-term exposure to the new antifoulant medetomidine
A Lennquist, N Asker, E Kristiansson, A Brenthel… - … and Physiology Part C …, 2011 - Elsevier
Medetomidine is under evaluation for use as an antifouling agent, and its effects on non-
target aquatic organisms are therefore of interest. In this study, rainbow trout was exposed to
low (0.5 and 5.0 nM) concentrations of medetomidine for up to 54days. Recently we have
reported on effects on paleness and melanophore aggregation of medetomidine in these
fish. Here, specific growth rates were investigated together with a broad set of physiological
parameters including plasma levels of growth hormone (GH), insulin-like growth factor-I (IGF …
target aquatic organisms are therefore of interest. In this study, rainbow trout was exposed to
low (0.5 and 5.0 nM) concentrations of medetomidine for up to 54days. Recently we have
reported on effects on paleness and melanophore aggregation of medetomidine in these
fish. Here, specific growth rates were investigated together with a broad set of physiological
parameters including plasma levels of growth hormone (GH), insulin-like growth factor-I (IGF …
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