Immunotherapy holds great promise for treatment of infectious and malignant diseases and
might help to prevent the occurrence and recurrence of cancer. We produced a plant-
derived tumor-associated colorectal cancer antigen EpCAM (pGA733) at high yields using
two modern plant expression systems. The full antigenic domain of EpCAM was efficiently
purified to confirm its antigenic and immunogenic properties as compared to those of the
antigen expressed in the baculovirus system (bGA733). Recombinant plant-derived antigen …