Up to half of patients with proximal deep vein thrombosis (DVT) will develop post-thrombotic
syndrome (PTS) despite optimal anticoagulant therapy. PTS significantly impacts upon
quality of life and has major health-economic implications. This narrative review describes
the pathophysiology, risk factors, and diagnosis, prevention and treatment of PTS, to
improve our understanding of the disease and guide treatment. Relevant articles were
identified through systematic searches of the PubMed, EMBASE and Cochrane databases …