Growing impact of poststroke upper extremity (UE) functional limitations entails newer dimensions in assessment methodologies. This has compelled researchers to think way beyond traditional stroke assessment scales during the out-patient rehabilitation phase. In concurrence with this, sensor-driven quantitative evaluation of poststroke UE functional limitations has become a fertile field of research. Here, we have emphasized an instrumented wearable for systematic monitoring of stroke patients with right-hemiparesis for evaluating their grasp abilities deploying intelligent algorithms. An instrumented glove housing 6 flex sensors, 3 force sensors, and a motion processing unit was developed to administer 19 activities of Action Research Arm Test (ARAT) while experimenting on 20 voluntarily participating subjects. After necessary signal conditioning, meaningful features were extracted, and subsequently the most appropriate ones were selected using the ReliefF algorithm. An optimally tuned support vector classifier was employed to classify patients with different degrees of disability and an accuracy of 92% was achieved supported by a high area under the receiver operating characteristic score. Furthermore, selected features could provide additional information that revealed the causes of grasp limitations. This would assist physicians in planning more effective poststroke rehabilitation strategies. Results of the one-way ANOVA test conducted on actual and predicted ARAT scores of the subjects indicated remarkable prospects of the proposed glove-based method in poststroke grasp ability assessment and rehabilitation.