Preservation of feather fibers from the Late Cretaceous dinosaur Shuvuuia deserti raises concern about immunohistochemical analyses on fossils
White fibers from a Late Cretaceous dinosaur Shuvuuia deserti stained positive for β-keratin
antibodies in a 1999 paper, followed by many similar immunological claims for Mesozoic
protein in bones and integument. Antibodies recognize protein epitopes derived from its
tertiary and quaternary structure, so such results would suggest long polypeptide
preservation allowing for sequencing with palaeobiological implications. However, proteins
are relatively unstable biomacromolecules that readily hydrolyze and amino acids exhibit …
antibodies in a 1999 paper, followed by many similar immunological claims for Mesozoic
protein in bones and integument. Antibodies recognize protein epitopes derived from its
tertiary and quaternary structure, so such results would suggest long polypeptide
preservation allowing for sequencing with palaeobiological implications. However, proteins
are relatively unstable biomacromolecules that readily hydrolyze and amino acids exhibit …
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