Introduction The relative rarity of mucosal melanomas of the head and neck (MMHN) has
made analysis of treatment approaches difficult. Advances in diagnostic techniques and
treatment interventions have had obvious impact on outcomes in cutaneous melanoma, but
the effects on outcome in MMHN remain undefined. This study aims to assess the outcome
and identify clinical and histologic prognostic indicators in a recent cohort of patients with
MMHN treated at a single institution. Methods The clinical records of 59 patients with the …

Diagnosis, therapy, and prognosis of 40 patients with malignant melanoma of the mucous
membranes, treated at one hospital from 1971 to 2006, were evaluated in a retrospective
study. The survival rate was compared with that established by the German-Austrian-Swiss
Study Group on Tumors of the Head and Neck (DÖSAK) for 121 cases. The cumulated 5-
year survival rate amounting to 33%(DÖSAK study 35%) emphasizes the unfavorable
prognosis of this tumor. Age, sex, or tumor location had no significant impact on a patient's …