Pro-resolving actions of SPM in adipose tissue biology
J Claria, C Lopez-Vicario, B Rius, E Titos - Molecular Aspects of Medicine, 2017 - Elsevier
White adipose tissue plays an important endocrine role in balancing metabolic homeostasis.
During conditions of nutrient excess, as occurs in obesity, there is an expansion of adipose
tissue mass associated with a state of “low-grade” inflammation in this tissue. This chronic,
unresolved inflammation of adipose tissue is deleterious and leads to many pathological
sequelae associated with obesity including insulin resistance, type 2 diabetes and non-
alcoholic fatty liver disease. Recently, a novel genus of anti-inflammatory and pro-resolving …
During conditions of nutrient excess, as occurs in obesity, there is an expansion of adipose
tissue mass associated with a state of “low-grade” inflammation in this tissue. This chronic,
unresolved inflammation of adipose tissue is deleterious and leads to many pathological
sequelae associated with obesity including insulin resistance, type 2 diabetes and non-
alcoholic fatty liver disease. Recently, a novel genus of anti-inflammatory and pro-resolving …
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