… However, the large volume of studies may paradoxically limit the generation of robust
evidence and complicate the formulation of trustworthy guidance and decisions related to
drug use if the current research is duplicative and redundant or produces conflicting data.Indeed,
the multiplicity of … We outline five priorities for greater collaboration and coordination
among trialists, meta-analysts, guideline developers, and other stakeholders to facilitate
producing and using trustworthy comparative evidence and guidance (table 1). These are …

Since the early days of the novel coronavirus outbreak, a record number of studies have
been launched to test several repurposed and new medicines as potential treatments for
covid-19 An analysis by the news organisation STAT identified over 1000 clinical trials
registered on ClinicalTrials. gov between January and June 2020. This is a testament to the
research and clinical community's commitment to identify effective treatments for covid-19.
However, the large volume of studies may paradoxically limit the generation of robust …