… To identify the prognostic significance of certain clinical, cellular and immunologic
markers in resectable non-small cell lung cancer (NSCLC). … Multivariate analyses using
the Cox proportional hazards model for survival confirmed AJCC stage (p < 0.001) in all
histologic subtypes to be the strongest factor of independent prognostic significance. It also
revealed the presence of CD20-stained B lymphocytes (p = 0.04) in the peritumoral region
of all tumours to be a positive … AJCC stage remains the most important prognostic …

Non–small cell lung cancer (NSCLC) comprises approximately four fifths of all primary lung
carcinomas in the United States. A greater number of individuals will have succumbed to
NSCLC than to colorectal and breast carcinomas combined in 1996. The latter diseases
represent the second and third most common causes of cancer mortality in the United
States, respectively. 56 Among those with NSCLC, the existence of resectable early-stage
disease is the most powerful predictor of outcome, outweighing all other prognostic factors …