Programmed cell death protein1 (PD1)‐targeted immunotherapy in advanced hepatocellular carcinoma: efficacy and safety data from an international multicentre …

B Scheiner, MM Kirstein, F Hucke… - Alimentary …, 2019 - Wiley Online Library
… In the present study, we aimed to analyse the safety and efficacy of anti-PD-1 … nivolumab
and pembrolizumab,19, 20 our cohort also includes patients with more advanced liver cirrhosis (…

Programmed Cell Death Protein1 (PD1)‐Targeted Immunotherapy for Advanced Hepatocellular Carcinoma in Real World

H Cui, G Dai, J Guan - OncoTargets and therapy, 2020 - Taylor & Francis
… In this retrospective research, we demonstrate that PD-1-targeted immunotherapy showed
promising efficacy and mild toxicity in a real-world cohort of patients with advanced stage HCC…

Programmed cell death protein-1 (PD-1)/programmed death-ligand-1 (PD-L1) axis in hepatocellular carcinoma: prognostic and therapeutic perspectives

T Mocan, Z Sparchez, R Craciun, CN Bora… - Clinical and …, 2019 - Springer
immunotherapy approaches, programmed cell death protein-… Indeed, agents targeting
PD-1/PD-L1 were recently reported … in decompensated chronic advanced liver diseases has also …

Programmed cell death protein 1 (PD-1)-inhibition in hepatocellular carcinoma (HCC): a single center experience

R Mahn, A Vogt, P Kupczyk, F Sadeghlar… - Scandinavian Journal …, 2020 - Taylor & Francis
… The prognosis for advanced Hepatocellular carcinoma (HCC)is … (PD-1), phase 3 trials failed
to show significant benefit of PD-… In summary, immunotherapy with PD-1 inhibition is feasible …

Real-world outcomes of patients with advanced intrahepatic cholangiocarcinoma treated with programmed cell death protein-1-targeted immunotherapy

M Deng, S Li, Q Wang, R Zhao, J Zou, W Lin… - Annals of …, 2022 - Taylor & Francis
… This research included 42 ICC patients who received PD-1-targeted immunotherapy
primary liver cancer. Tumour development and antitumor treatments may affect liver function…

[HTML][HTML] PD-1/PD-L1 checkpoint inhibitors in advanced hepatocellular carcinoma immunotherapy

Q Li, J Han, Y Yang, Y Chen - Frontiers in Immunology, 2022 - frontiersin.org
immunotherapy, and the introduction of immune checkpoint inhibitors has brought fundamental
changes to the treatment of HCC. Programmed cell death protein 1 (PD-1… , we focused on …

[HTML][HTML] Predicting hyperprogressive disease in patients with advanced hepatocellular carcinoma treated with anti-programmed cell death 1 therapy

L Zhang, L Wu, Q Chen, B Zhang, J Liu, S Liu… - …, 2021 - thelancet.com
… carcinoma (HCC) treated with programmed cell death 1 (PD-1) inhibitors. We aimed to …
this study, 10 (14·49%) patients with advanced HCC treated with anti-PD-1 immunotherapy

[HTML][HTML] Immunologic features of patients with advanced hepatocellular carcinoma before and during sorafenib or anti-programmed death-1/programmed death-L1 …

ZM Jilkova, C Aspord, K Kurma, A Granon… - Clinical and …, 2019 - journals.lww.com
… immune responses via immunotherapies serves as a … HCC is an important target for
immunotherapy as chronic liver … In this study, we focused on a cohort of patients with advanced-…

Efficacy and safety of anti-programmed cell death protein-1 immunotherapy for advanced hepatocellular carcinoma with pulmonary metastases: a single-center …

M Zhao, Y Zhang, H Wang, P Liu… - Technology in Cancer …, 2021 - journals.sagepub.com
… -programmed cell death protein-1 immunotherapy has been approved as a new treatment
option for advanced hepatocellular … Furthermore, immunotherapy in combination with targeted

[PDF][PDF] Programmed cell death1 (PD1) checkpoint blockade in combination with a mammalian target of rapamycin inhibitor restrains hepatocellular carcinoma …

H Li, X Li, S Liu, L Guo, B Zhang, J Zhang, Q Ye - Hepatology, 2017 - Wiley Online Library
… respond to anti-PD-1 immunotherapy. Here, we show that … (10) PD-1 expressed on T
cells binds to its ligands PDL1 (B7-… unprecedented response rates in advanced liver cancer.(47) …