… on programmed cell death protein 1 (PD‑1) and programmed … first-line treatment of advanced
liver cancer based on the results of … eight drugs targeting PD-1 and PD-L1 developed in the …

… Molecular targeted drugs and immunotherapy might be an effective option to decrease …
of programmed death protein-1 (PD-1) inhibitors such as nivolumab and pembrolizumab for …

… This study aimed to clarify the mechanism for optimal patient … (13) Patients included showed
Barcelona Clinic Liver Cancer … shortened the PDL1 protein half- life in HCCLM3 cells (Fig. 3A…

… The efficacy of targeted programmed cell death 1/programmed death ligand 1 (PD-1/PD-L1)
monoclonal antibodies (… Immunotherapy is a promising treatment of malignant tumors and …

… ) is regarded as a predicting factor of clinical response to anti-PD-1 axis immunotherapy. …
, we aimed to define the biological and clinical relevance of the expressions of PD-L1 and PD-…

… -PD-1 mAb, drugs targeting other immune checkpoints include cytotoxic T-lymphocyte associated
protein-4 (CTLA-4), programmed cell death-1 (PD-1) … of CD8 + T cells is suppressed by …

… between the HCC and normal tissues, so we focused on the epigenetic modulations at IRF8
gene focus… Pembrolizumab as second- line therapy in patients with advanced hepatocellular …

Frontiers | Efficacy and safety of hepatic arterial infusion chemotherapy combined with
programmed cell death protein-1 antibody and lenvatinib for advanced hepatocellular carcinoma …

… lesion, which was mainly located in the left hemi-liver and invaded the left branch of portal
vein. (… of PD-L1 and a higher TMB in molecular targeted therapy and immunotherapy were not …

… Nivolumab, an immunotherapeutic agent to block programmed cell death protein 1 (PD-1), …
pathway and can be targeted to shape the immune responses of the liver, for example, …