Tropical cyclone (TC) is an important research area since it has a significant impact on human life, properties and environment. The researchers all over the world have been studying fundamental and advanced processes to better understand and thereby predict the genesis and evolution of TCs. This review chapter provides a brief overview on TC climatology, their basic characteristics, movement and intensification, research on structure analysis and prediction of these fascinating storms, with primary emphasis to North Indian Ocean (NIO). The role of ocean and atmosphere in determining the genesis and intensification of TCs is discussed. This chapter reviews the past and current research activities including inter-annual and intra-seasonal changes in TCs, current status of TC research using numerical weather prediction, gaps identified and relevant measures taken by the meteorological and government agencies in this direction, along with future directions in order to improve the understanding and predictability over the NIO region.