Prolonged sleep deprivation decreases cell proliferation and immature newborn neurons in both dorsal and ventral hippocampus of male rats

Y Murata, A Oka, A Iseki, M Mori, K Ohe, K Mine… - Neuroscience …, 2018 - Elsevier
Previous studies have indicated that sleep deprivation negatively affects hippocampal
neurogenesis, which may explain the reason for the relation between sleep loss and
depression. Increasing evidence indicates that the hippocampus is anatomically and
functionally segregated along a dorsolateral (cognitive function)/ventromedial (control for
mood and stress response) axis. Thus, the present study was conducted to elucidate
regional differences in the adverse effects of sleep deprivation on hippocampal …
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