Prospective association of white matter hyperintensity volume and frailty in older adults
M Maltais, P de Souto Barreto, SY Moon… - Experimental …, 2019 - Elsevier
Background Frailty is a prevalent geriatric condition and its association with brain health is
still weakly investigated. The objective of this study was to examine whether brain white
matter hyperintensities (WMH) were related to longitudinal changes in frailty severity in
community-dwelling older adults. Methods 113 community-dwelling older adults, aged 70
years and over, enrolled in the placebo group from the 3-year Multidomain Alzheimer's
Preventive Trial (MAPT). Frailty was assessed using Fried's frailty phenotype as an ordinal …
still weakly investigated. The objective of this study was to examine whether brain white
matter hyperintensities (WMH) were related to longitudinal changes in frailty severity in
community-dwelling older adults. Methods 113 community-dwelling older adults, aged 70
years and over, enrolled in the placebo group from the 3-year Multidomain Alzheimer's
Preventive Trial (MAPT). Frailty was assessed using Fried's frailty phenotype as an ordinal …
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