Proteomic analysis of heparin-binding proteins from human seminal plasma: a step towards identification of molecular markers of male fertility

V Kumar, MI Hassan, AK Tomar, T Kashav… - Journal of …, 2009 - Springer
Glycosaminoglycans, especially heparin, are involved in various cell processes such as
apoptosis, cell cycle control, platelet activation, capacitation, acrosome reaction and sperm
decondensation. Heparin-binding proteins (HBPs) are essential constituents of human
seminal fluid, which bind to sperm lipids containing the phosphorylcholine group and
mediate the fertilization process. We utilized a proteomic set-up consisting of affinity
chromatography, isoelectric focusing (IEF) coupled with matrix-assisted laser …

Proteomic analysis of heparin-binding proteins from human seminal plasma: a step towards identification of molecular markers of male fertility.

VK Vijay Kumar, MI Hassan, AK Tomar… - 2009 - cabidigitallibrary.org
Glycosaminoglycans, especially heparin, are involved in various cell processes such as
apoptosis, cell cycle control, platelet activation, capacitation, acrosome reaction and sperm
decondensation. Heparin-binding proteins (HBPs) are essential constituents of human
seminal fluid, which bind to sperm lipids containing the phosphorylcholine group and
mediate the fertilization process. We utilized a proteomic set-up consisting of affinity
chromatography, isoelectric focusing (IEF) coupled with matrix-assisted laser …
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