… in the present study, the fenfluramine-associated pulmonary arterial hypertension group and
the group of idiopathic and familial pulmonary arterial hypertension groups were compared …

… : Several case reports have linked some monoclonal … Phentermine was often prescribed in
conjunction with fenfluramine … Both studies concluded that exposure to the SSRI class after 20 …

… matched PAH patients non-exposed to fenfluramine, patients with fenfluramine-induced PAH
had … reported 85 cases of pulmonary hypertension associated with benfluorex exposure, 70 …

… PAH patients not exposed to fenfluramine, patients with fenfluramine-… 85 cases of PH
associated with benfluorex exposure … The median delay between initiation of benfluorex exposure …

… fenfluramine exposure was 6 months, with a median of 4.5 years between exposure and onset
of symptoms among 109 … In all such cases, the exposure to benfluorex came after the use …

… to be a cause of pulmonary arterial hypertension (PAH). … with the cohort with fenfluramine
exposure, patients exposed to … for mean PAP and pulmonary vascular resistance. We also …

… report found that use of anorexigens, such as fenfluramine … could combine with fenfluramine
exposure to greatly increase … changes of vascular remodeling109. Phenylpropanolamine …

… According to the current classification, PAH can be associated with exposure to certain …
fenfluramine and are considered to have Similar risk of DIPAH as reported in several case reports …

… in 1972 following these case reports but remained on the … a strong association between
fenfluramine exposure and PH. … can induce endothelial cell apoptosis (109) and also can trigger …

… 23 Souza R, Humbert M, Sztrymf B, Jais X, Yaici A, Le Pavec J, et al: Pulmonary arterial
hypertension associated with fenfluramine exposure: report of 109 cases. Eur Respir J 2008;31:…