… This review has highlighted the medicinal value of pyridopyrimidine moiety utilizing single
step multi-component and microwave assisted synthetic methodology to give pyridopyrimidine …

… dual ErbB2/EGFR tyrosine kinase inhibitors were studied as potential anticancer agents [145].
However, the pyridopyrimidine ErB2 inhibitor 256 was found to be 200 fold more selective …

… of applications in anticancer drug development. … anticancer properties characterized in vitro
or through in silico studies and illustrates their potential in development of anticancer agents. …

… ), with potential anticancer activity. An initial in vitro screening of 60 cancer cell lines identified
pyridopyrimidine derivatives 9a-g as promising broad-spectrum anticancer agents, with …

… anticancer agents, and will help scientists to design new selective, effective and safe anticancer
agents. … Fusing a pyridine and a pyrimidine ring results in pyridopyrimidines, ortho-fused …

… The pyridopyrimidine compounds are a group of fused heterocycles that possess various …
that involved synthesis of different other substituted pyridopyrimidine compounds [20–22] and …

… of novel small molecules as anticancer agents. Electron donating … of new small molecules
as anticancer agents. Electron donating … to design and develop new potent anticancer agents. …

… derivatives pyridopyrimidines were least focused. Hence, in this review helpful to design
and novel pyridopyrimidine derivatives, proceeding molecular docking studies for anticancer …

… anticancer agents. Among the wide range of compounds tested as potential anticancer agents…
Analysis of the data in Table 2 showed that, 2-(2-arylidenehydrazinyl)pyridopyrimidines 5a…

… pyridopyrimidine analogs are well-known heterocyclic compounds used in cancer chemotherapy
[28,29]. For example, the pyridopyrimidine … as a promising anticancer agent. Therefore, …