Quantifying assays: inhibition of signalling pathways of cancer
Inhibiting a signalling pathway concerns controlling the cellular processes of a cancer cell's
viability, cell division and death. Assay protocols created to see if the molecular structures of
the drugs being tested have the desired inhibition qualities often show great variability
across experiments, and it is imperative to diminish the effects of such variability while
inferences are drawn. In this paper, we propose the study of experimental data through the
lenses of a mathematical model depicting the inhibition mechanism and the activation …
viability, cell division and death. Assay protocols created to see if the molecular structures of
the drugs being tested have the desired inhibition qualities often show great variability
across experiments, and it is imperative to diminish the effects of such variability while
inferences are drawn. In this paper, we propose the study of experimental data through the
lenses of a mathematical model depicting the inhibition mechanism and the activation …
[PDF][PDF] Quantifying assays: Inhibition of signalling pathways
Inhibiting a signalling pathway concerns controlling the cellular processes of 5 a cancer
cell's viability, cell division, and death. Assay protocols created to see 6 if the molecular
structures of the drugs being tested have the desired inhibition 7 qualities often show great
variability across experiments, and it is imperative to 8 diminish the effects of such variability
while inferences are drawn. In this paper we 9 propose the study of experimental data
through the lenses of a mathematical model 10 depicting the inhibition mechanism and the …
cell's viability, cell division, and death. Assay protocols created to see 6 if the molecular
structures of the drugs being tested have the desired inhibition 7 qualities often show great
variability across experiments, and it is imperative to 8 diminish the effects of such variability
while inferences are drawn. In this paper we 9 propose the study of experimental data
through the lenses of a mathematical model 10 depicting the inhibition mechanism and the …
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