Quantitative investigation on correlation between IgG and FcRn during gestation and lactating periods in rat

Y Wang, X Jiang, J He, T Diraviyam… - American Journal of …, 2016 - Wiley Online Library
Problem IgG is transformed from maternal serum into the offspring as passive immunization
by FcRn expressed in placenta and/or infant intestine. This study aimed to investigate the
quantitative correlation between IgG and FcRn during gestation and lactating periods in rat.
Method of Study ELISA was performed to determine the variation of maternal and offspring
IgG. Western blot and RT‐qPCR were carried out to characterize FcRn expression in
placenta and infant intestine. Results Maternal serum IgG appeared higher in first 2 weeks of …

Quantitative investigation on correlation between IgG and FcRn during gestation and lactating periods in rat.

WY Wang Yuan, JXM Jiang XueMei, HJX He JinXin… - 2016 - cabidigitallibrary.org
Problem: IgG is transformed from maternal serum into the offspring as passive immunization
by FcRn expressed in placenta and/or infant intestine. This study aimed to investigate the
quantitative correlation between IgG and FcRn during gestation and lactating periods in rat.
Method of Study: ELISA was performed to determine the variation of maternal and offspring
IgG. Western blot and RT-qPCR were carried out to characterize FcRn expression in
placenta and infant intestine. Results: Maternal serum IgG appeared higher in first 2 weeks …
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