Quantitative optical tomography of sub-surface heterogeneities using spatially modulated structured light

SD Konecky, A Mazhar, D Cuccia, AJ Durkin… - Optics express, 2009 - opg.optica.org
Optics express, 2009opg.optica.org
We present a wide-field method for obtaining three-dimensional images of turbid media. By
projecting patterns of light of varying spatial frequencies on a sample, we reconstruct
quantitative, depth resolved images of absorption contrast. Images are reconstructed using a
fast analytic inversion formula and a novel correction to the diffusion approximation for
increased accuracy near boundaries. The method provides more accurate quantification of
optical absorption and higher resolution than standard diffuse reflectance measurements.
We present a wide-field method for obtaining three-dimensional images of turbid media. By projecting patterns of light of varying spatial frequencies on a sample, we reconstruct quantitative, depth resolved images of absorption contrast. Images are reconstructed using a fast analytic inversion formula and a novel correction to the diffusion approximation for increased accuracy near boundaries. The method provides more accurate quantification of optical absorption and higher resolution than standard diffuse reflectance measurements.
opg.optica.org
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