One enigma in biology is the generation, sensing and maintenance of membrane curvature.
Curvature-mediating proteins have been shown to induce specific membrane shapes by
direct insertion and nanoscopic scaffolding, while the cytoskeletal motors exert forces
indirectly through microtubule and actin networks. It remains unclear, whether the manifold
direct motorprotein–lipid interactions themselves constitute another fundamental route to
remodel the membrane shape. Here we show, combining super-resolution-fluorescence …

The generation, sensing and maintenance of membrane curvature is key to many cellular
motile processes. A fundamental problem of molecular cell biology in conjunction with
physics and mathematics is therefore to understand the evolutionary, developmental and
functional rationale for these membrane shapes, as well as the mechanisms used by cells to
produce them. Curvature-mediating proteins have been shown to induce specific membrane
shapes by direct insertion and nanoscopic scaffolding, while cytoskeletal motors exert forces …