Reduction of dietary phosphorus absorption by phosphorus binders. A theoretical, in vitro, and in vivo study.
MS Sheikh, JA Maguire, M Emmett… - The Journal of …, 1989 - Am Soc Clin Investig
Antacids used to decrease phosphorus absorption in patients with renal failure may be toxic.
To find more efficient or less toxic binders, a three-part study was conducted. First,
theoretical calculations showed that phosphorus binding occurs in the following order of
avidity: Al3+ greater than H+ greater than Ca2+ greater than Mg2+. In the presence of acid
(as in the stomach), aluminum can therefore bind phosphorus better than calcium or
magnesium. Second, in vitro studies showed that the time required to reach equilibrium …
To find more efficient or less toxic binders, a three-part study was conducted. First,
theoretical calculations showed that phosphorus binding occurs in the following order of
avidity: Al3+ greater than H+ greater than Ca2+ greater than Mg2+. In the presence of acid
(as in the stomach), aluminum can therefore bind phosphorus better than calcium or
magnesium. Second, in vitro studies showed that the time required to reach equilibrium …
[引用][C] Reduction of dietary phosphorus absorption by phosphorus binders. A theoretical in vitro and in vivo study by MS Sheikh, JA Maguire, M Emmett, CA Santa Ana …
JA Walker - Seminars in Dialysis, 1989 - Wiley Online Library
Reduction of dietary phosphorus absorption by phosphorus binders. A theoretical in vitro
and in vivo study by MS Sheikh, JA Maguire, M Emmett, CA Santa Ana, MJ Nicar, LR Schiller,
and JS Fordtran. - Walker - 1989 - Seminars in Dialysis - Wiley Online Library …
and in vivo study by MS Sheikh, JA Maguire, M Emmett, CA Santa Ana, MJ Nicar, LR Schiller,
and JS Fordtran. - Walker - 1989 - Seminars in Dialysis - Wiley Online Library …
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