Relationship between human papillomavirus status and the cervicovaginal microbiome in cervical cancer
Uterine cervical cancer (CC) is a complex, multistep disease primarily linked to persistent
infection with high-risk human papillomavirus (HR-HPV). However, it is widely
acknowledged that HR-HPV infection alone cannot account for the formation and
progression of CC. Emerging evidence suggests that the cervicovaginal microbiome (CVM)
also plays a significant role in HPV-related CC. Certain bacteria, such as Fusobacterium
spp., Porphyromonas, Prevotella, and Campylobacter, are currently being considered as …
infection with high-risk human papillomavirus (HR-HPV). However, it is widely
acknowledged that HR-HPV infection alone cannot account for the formation and
progression of CC. Emerging evidence suggests that the cervicovaginal microbiome (CVM)
also plays a significant role in HPV-related CC. Certain bacteria, such as Fusobacterium
spp., Porphyromonas, Prevotella, and Campylobacter, are currently being considered as …
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