… renoprotective effects, including hypoxia-related pathways in humans, SGLT2 inhibitor effects
… Similar to findings in animals, SGLT2 inhibition reduces hyperfiltration in patients with T1D.…

… , which appeared to be partly independent of the original glucoselowering effect. SGLT2
inhibitors have both direct and indirect renoprotective effects. The direct effects involve the …

… inhibitors protect against the progression of kidney disease through pleiotropic effects (…
mechanisms associated with the renoprotective effect of SGLT2 inhibitors, primarily focusing on …

… Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a novel class of glucose-lowering
agents with potential renoprotective effects. Key Message: SGLT2 inhibitors represent a …

… intrarenal hemodynamic effects of SGLT2 inhibitors are markedly … Yet, SGLT2 inhibitors
exert meaningful renoprotective effects … This observation suggests that the SGLT2 inhibitors to …

… review on the renoprotective effect of sodiumglucose cotransporter 2 inhibitor (SGLT2i) [1], …
However, the underlying mechanisms for the renoprotective effect of SGLT2i remain largely …

Aims We undertook a systematic review and meta‐analysis to assess the efficacy and safety
of sodium‐glucose cotransporter 2 inhibitors (SGLT2is) concerning kidney outcomes in …

… by which SGLT2 inhibitors exert beneficial effects on the renal and … by which SGLT2
inhibitors exert a renoprotective effect. In … in renal hemodynamics induced by SGLT2 inhibition. …

… for renoprotection as a possible, unintended consequence of the sodium–glucose liked
transporter 2 (SGLT2) inhibitors. … and safety of sodium glucose cotransporter-2 inhibitors in adults …

Background Sodium-glucose cotransporter 2 inhibitor (SGLT2i) reduces the risk of the
composite renal endpoint and weakens the progressive decline in renal function in patients with …