Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils

D Pérez-Acuña, KH Rhee, SJ Shin, J Ahn… - Acta neuropathologica …, 2023 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the aggregation
of misfolded α-synuclein and progressive spreading of the aggregates from a few discrete
regions to wider brain regions. Although PD has been classically considered a movement
disorder, a large body of clinical evidence has revealed the progressive occurrence of non-
motor symptoms. Patients present visual symptoms in the initial stages of the disease, and
accumulation of phospho-α-synuclein, dopaminergic neuronal loss, and retinal thinning has …

Correction: Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils

D Pérez-Acuña, KH Rhee, SJ Shin, J Ahn… - Acta Neuropathologica …, 2024 - Springer
Following publication of the original article [1], the authors have identified that an error was
present in two of the images. Figure 1 D and Figure 5 E have incorrect representative
images. The authors have revised the data and verified that such an error does not affect the
integrity and accuracy of the content presented in the article. For figure 1 D 7 days pi PBS
and PFF, although images belong to the indicated experimental group, lower magnification
images do not correspond to the zoomed magnification images. For clarification, correct …
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