Risk stratification and long‐term risk prediction of E6 oncoprotein in a prospective screening cohort in C hina
Q Zhang, L Dong, S Hu, R Feng… - … journal of cancer, 2017 - Wiley Online Library
E6 oncoprotein is a necessary agent of HPV driven oncogenic transformation. This study is
aimed at evaluating the risk stratification potency of HPV 16/18 E6 oncoprotein (E6) as a
triage method for HPV positivity. Moreover, it also acts as a predictor of cervical
intraepithelial neoplasia grade 3 or worse (CIN3+). The screening cohort of 1,997 women
was followed for a 15 year period in approximate five‐year intervals. Participants were
concurrently screened by HPV DNA testing (HC2), liquid based cytology (LBC), visual …
aimed at evaluating the risk stratification potency of HPV 16/18 E6 oncoprotein (E6) as a
triage method for HPV positivity. Moreover, it also acts as a predictor of cervical
intraepithelial neoplasia grade 3 or worse (CIN3+). The screening cohort of 1,997 women
was followed for a 15 year period in approximate five‐year intervals. Participants were
concurrently screened by HPV DNA testing (HC2), liquid based cytology (LBC), visual …
Risk stratification and long-term risk prediction of E6 oncoprotein in a prospective screening cohort in China.
ZQ Zhang Qian, DL Dong Li, HSY Hu ShangYing… - 2017 - cabidigitallibrary.org
E6 oncoprotein is a necessary agent of HPV driven oncogenic transformation. This study is
aimed at evaluating the risk stratification potency of HPV 16/18 E6 oncoprotein (E6) as a
triage method for HPV positivity. Moreover, it also acts as a predictor of cervical
intraepithelial neoplasia grade 3 or worse (CIN3+). The screening cohort of 1,997 women
was followed for a 15 year period in approximate five-year intervals. Participants were
concurrently screened by HPV DNA testing (HC2), liquid based cytology (LBC), visual …
aimed at evaluating the risk stratification potency of HPV 16/18 E6 oncoprotein (E6) as a
triage method for HPV positivity. Moreover, it also acts as a predictor of cervical
intraepithelial neoplasia grade 3 or worse (CIN3+). The screening cohort of 1,997 women
was followed for a 15 year period in approximate five-year intervals. Participants were
concurrently screened by HPV DNA testing (HC2), liquid based cytology (LBC), visual …
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