Robustness: mechanisms and consequences

J Masel, ML Siegal - Trends in genetics, 2009 - cell.com
… Whatever its mechanism or origin, robustness to mutation … Partial robustness can lead to
pre-adaptation, and thereby … robustness – are critical to understanding the mechanisms and …

On the nature and evolutionary impact of phenotypic robustness mechanisms

ML Siegal, JY Leu - Annual review of ecology, evolution, and …, 2014 - annualreviews.org
… This review aims to synthesize current understanding of robustness mechanisms and to
cut … about mutational robustness. Some studies have confused mutational robustness with …

Biological robustness

H Kitano - Nature Reviews Genetics, 2004 - nature.com
… against natural and therapeutic countermeasures if intrinsic mechanisms for robustness in …
maintained against countermeasures: the mechanisms that support robustness of the host are …

Mechanisms of developmental robustness

VV Gursky, SY Surkova, MG Samsonova - Biosystems, 2012 - Elsevier
… We present a review of noise buffering mechanisms responsible for developmental robustness.
We focus on functions of chaperone Hsp90, miRNA, and cross-regulation of gap genes …

Robustness and evolvability

J Masel, MV Trotter - Trends in Genetics, 2010 - cell.com
Robustness can be defined and measured as the average effect of a specified perturbation
on a specified phenotype. Here, we focus on genetic robustness, ie robustness … of robustness

Robustness and evolution: concepts, insights and challenges from a developmental model system

MA Félix, A Wagner - Heredity, 2008 - nature.com
… causes of robustness, namely redundancy and distributed robustness. We … mechanisms
underlying robustness. Finally, we discuss evolutionary causes and consequences of robustness

Molecular mechanisms governing differential robustness of development and environmental responses in plants

J Lachowiec, C Queitsch, DJ Kliebenstein - Annals of botany, 2016 - academic.oup.com
… recently identified mechanisms, both systems-level and molecular, that modulate robustness,
and discusses their implications for the optimization of plant fitness. Robustness in living …

Molecular mechanisms of robustness in plants

J Lempe, J Lachowiec, AM Sullivan… - Current opinion in plant …, 2013 - Elsevier
… supports an important role of robustness in the genotype to … Similar to animals and fungi,
plant robustness is a function of … in identifying molecular robustness mechanisms in plants …

Robustness in machine learning explanations: does it matter?

L Hancox-Li - Proceedings of the 2020 conference on fairness …, 2020 - dl.acm.org
… I argue that robustness is desirable to the extent that we’re concerned about finding real
patterns in the world. The import of real patterns differs according to the problem context. In …

Pervasive robustness in biological systems

MA Félix, M Barkoulas - Nature Reviews Genetics, 2015 - nature.com
robustness mechanisms. Below, we present designs to study robustness, successively
for different types of incoming variation, using induced mutants or natural genetic variation. …