Minerals and organic materials present in soil are responsible for regulatory activity of cell organelles. Micronutrients such as zinc, boron, copper, iron, manganese, molybdenum and chlorine are readily absorbed and found in lower concentrations in plant tissues. Micronutrients reduce ion toxicity, preserve water balance, improve mineral uptake and assimilation, modify various gas exchange traits and reduce oxidative stress in plants. Plants contain sufficient micronutrients that possess greater tolerance capacity towards abiotic stress. The response of micronutrient application to various abiotic stresses depends on the crop, growth stage and concentration of the nutrient solution. This chapter explains the significance of micronutrients in crop production and their ability against the abiotic stress in plants.