Role of senescence marker p16INK4a measured in peripheral blood T-lymphocytes in predicting length of hospital stay after coronary artery bypass surgery in older …

A Pustavoitau, V Barodka, NE Sharpless… - Experimental …, 2016 - Elsevier
Adults older than 65 years undergo more than 120,000 coronary artery bypass (CAB)
procedures each year in the United States. Chronological age alone, though commonly
used in prediction models of outcomes after CAB, does not alone reflect variability in aging
process; thus, the risk of complications in older adults. We performed a prospective study to
evaluate a relationship between senescence marker p16 INK4a expression in peripheral
blood T-lymphocytes (p16 levels in PBTLs) with aging and with perioperative outcomes in …
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