SFTG international collaborative study on in vitro micronucleus test: II. Using human lymphocytes
MG Clare, G Lorenzon, LC Akhurst, D Marzin… - … /Genetic Toxicology and …, 2006 - Elsevier
This study on the in vitro micronucleus assay, comprising 11 laboratories using human
lymphocytes, was coordinated by an organizing committee supported by the SFTG (the
French branch of the European Environmental Mutagen Society). Nine coded substances
were assessed for their ability to induce micronuclei in human lymphocytes in vitro,
mitomycin C being used as a positive control. Cultures were exposed to the test substances
for a short (early or late) time or for a long time, followed by a short or long recovery period …
lymphocytes, was coordinated by an organizing committee supported by the SFTG (the
French branch of the European Environmental Mutagen Society). Nine coded substances
were assessed for their ability to induce micronuclei in human lymphocytes in vitro,
mitomycin C being used as a positive control. Cultures were exposed to the test substances
for a short (early or late) time or for a long time, followed by a short or long recovery period …
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