Safety and tumor tissue accumulation of pegylated graphene oxide nanosheets for co-delivery of anticancer drug and photosensitizer

W Miao, G Shim, S Lee, S Lee, YS Choe, YK Oh - Biomaterials, 2013 - Elsevier
… the safety, tumor accumulation and potential of polyethylene glycol-grafted graphene oxide
(… First, both graphene oxide (GO) and pGO were synthesized, and their in vitro and in vivo …

Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: Stimuli-responsive carriers, co-delivery and suppressing resistance

M Ashrafizadeh, H Saebfar, MH Gholami… - Expert opinion on …, 2022 - Taylor & Francis
… DOX from tissues requires more time than its distribution [Citation… A recent experiment
has developed PEGylated platinum … strategies for modification of GO nanosheets is layer-by-layer …

[HTML][HTML] SiRNA delivery with PEGylated graphene oxide nanosheets for combined photothermal and genetherapy for pancreatic cancer

F Yin, K Hu, Y Chen, M Yu, D Wang, Q Wang… - Theranostics, 2017 - ncbi.nlm.nih.gov
… We have previously shown that the co-delivery of siRNA and … nanocomplexes preferentially
accumulated in tumor sites. … /siRNA nanoformulations-treated tumor tissues were detected by …

Graphene-based nanosheets for delivery of chemotherapeutics and biological drugs

G Shim, MG Kim, JY Park, YK Oh - Advanced drug delivery reviews, 2016 - Elsevier
… For enhanced distribution to specific tissues, GNS have been covalently or non-… PEGylated
rGO provided higher interaction energy and loading of single stranded RNA than PEGylated

PEGylated graphene oxide for tumor-targeted delivery of paclitaxel

H Xu, M Fan, AMA Elhissi, Z Zhang, KW Wan… - …, 2015 - Future Medicine
… The tissue distribution and anticancer efficacy of GO-PEG-PTX were then investigated using
… According to these results, GO-PEG-PTX has shown to be safe for in vivo administration at …

[HTML][HTML] PEGylated nano-graphene oxide as a nanocarrier for delivering mixed anticancer drugs to improve anticancer activity

X Pei, Z Zhu, Z Gan, J Chen, X Zhang, X Cheng… - Scientific reports, 2020 - nature.com
… of co-delivery of Pt and DOX by PEGylated nano-graphene … We demonstrated that pGO
nanosheets had enhanced … system accumulation and improved tumor passive targeting effect. …

[HTML][HTML] Multifunctionalization of graphene and graphene oxide for controlled release and targeted delivery of anticancer drugs

CC Liu, JJ Zhao, R Zhang, H Li, B Chen… - American journal of …, 2017 - ncbi.nlm.nih.gov
… obtained pGO nanosheets showed higher safety and improved … /DOX nanosheets resulted
in higher tumor accumulation and … -PEI-PEG carrier led to marked regression of tumor growth …

Graphene oxide and reduced graphene oxide: Efficient cargo platforms for cancer theranostics

F Alemi, R Zarezadeh, AR Sadigh… - Journal of Drug Delivery …, 2020 - Elsevier
… of siRNA to liver tumor tissues by GO-PEG nanocarrier [86]. … They found that MnO 2 -FA-GO
nanosheets were significantly … to increase the accumulation of Ce6 in tumor cells and …

Functionalized graphene oxide as a vehicle for targeted drug delivery and bioimaging applications

N Karki, H Tiwari, C Tewari, A Rana… - Journal of Materials …, 2020 - pubs.rsc.org
… in tumor tissue from the brain demonstrated that Tf–PEG–GO… a promising strategy through
co-delivery of drugs within the … on the surface of GO nanosheets in the presence of PEG. A …

Redox-sensitive prodrug molecules meet graphene oxide: an efficient graphene oxide-based nanovehicle toward cancer therapy

N Ma, A Song, Z Li, Y Luan - ACS Biomaterials Science & …, 2019 - ACS Publications
… in vivo distribution with a higher accumulation in cancer cells and … Therefore, it is of
importance to study the safety of our fabricated … In summary, a new nanovehicle of PEG-PCL-SS-DOX …