Salt stress effects on the central and carnitine metabolisms of Escherichia coli
The aim was to understand how interaction of the central carbon and the secondary
carnitine metabolisms is affected under salt stress and its effect on the production of l‐
carnitine by Escherichia coli. The biotransformation of crotonobetaine into l‐carnitine by
resting cells of E. coli O44 K74 was improved by salt stress, a yield of nearly twofold that for
the control being obtained with 0.5 M NaCl. Crotonobetaine and the l‐carnitine formed acted
as an osmoprotectant during cell growth and biotransformation in the presence of NaCl. The …
carnitine metabolisms is affected under salt stress and its effect on the production of l‐
carnitine by Escherichia coli. The biotransformation of crotonobetaine into l‐carnitine by
resting cells of E. coli O44 K74 was improved by salt stress, a yield of nearly twofold that for
the control being obtained with 0.5 M NaCl. Crotonobetaine and the l‐carnitine formed acted
as an osmoprotectant during cell growth and biotransformation in the presence of NaCl. The …
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