Salvia miltiorrhiza and Pueraria lobata, two eminent herbs in Xin-Ke-Shu, ameliorate myocardial ischemia partially by modulating the accumulation of free fatty acids …

L Sun, H Jia, M Yu, Y Yang, J Li, D Tian, H Zhang… - Phytomedicine, 2021 - Elsevier
Abstract Background Xin-Ke-Shu (XKS), a commonly used traditional Chinese medicine,
has been clinically proven to be effective for treatment of acute myocardial ischemia (AMI).
Numerous studies underscore the important role of fatty acid metabolism in the
pathogenesis of AMI. Purpose This study examined the relationship between free fatty acids
(FFAs) and AMI and the contributions of individual herbs found in XKS to provide a basis for
the study of the compatible principle of XKS. Methods UFLC-MS/MS-based targeted …
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