[HTML][HTML] Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways
Schistosoma mansoni (Sm) infection has been linked with an increased risk of HIV
acquisition in women. Therefore, defining the mechanism (s) by which Sm alters HIV
susceptibility might lead to new HIV prevention strategies. Here, we analyze the impact of
standard Sm therapy in HIV-uninfected Sm+ Ugandan adult women on genital HIV
susceptibility and mucosal and systemic immunology. Schistosomiasis treatment induces a
profound reduction of HIV entry into cervical and blood CD4+ T cells that is sustained for up …
acquisition in women. Therefore, defining the mechanism (s) by which Sm alters HIV
susceptibility might lead to new HIV prevention strategies. Here, we analyze the impact of
standard Sm therapy in HIV-uninfected Sm+ Ugandan adult women on genital HIV
susceptibility and mucosal and systemic immunology. Schistosomiasis treatment induces a
profound reduction of HIV entry into cervical and blood CD4+ T cells that is sustained for up …
以上显示的是最相近的搜索结果。 查看全部搜索结果