Screening and Characterization of Streptomyces spp. Isolated from Three Moroccan Ecosystems Producing a Potential Inhibitor of the Drug Efflux Pump AcrAB-TolC

A Azmani, S Lemriss, M Barakate, A Souiri, D Dhiba… - BioTech, 2022 - mdpi.com
Traditional antimicrobial antibiotics are increasingly suffering from the emergence of
multidrug resistance among pathogenic microorganisms. The antibiotic era is threatened by
the ruthless rise of resistance in bacterial infections. A significant role in these resistance
profiles is attributed to multidrug efflux pumps. Hence, much effort is being directed towards
developing new compounds to overcome this problem. During our screening program of
efflux pumps inhibitors (EPI) produced by bioactive Moroccan Actinobacteria, 210 isolates …

[PDF][PDF] Screening and Characterization of Streptomyces spp. Isolated from three Moroccan Ecosystems Producing a Potential Inhibitor of The Drug Efflux Pump AcrAB …

A Azmani, S Lemriss, M Barakate, A Souiri, D Dhiba… - 2022 - academia.edu
Traditional antimicrobial antibiotics are increasingly suffering from the emergence of
multidrug resistance among pathogenic microorganisms. The antibiotic era is threatened by
the ruthless rise of resistance in bacterial infections. A significant role in these resistance
profiles is attributed to multidrug efflux pumps. Hence, much effort is being directed towards
developing new compounds to overcome this problem. During our screening program of
efflux pumps inhibitors (EPI) produced by bioactive Moroccan Actinobacteria, 210 isolates …
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