Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis
R Smith-Bindman, W Hosmer, VA Feldstein, JJ Deeks… - Jama, 2001 - jamanetwork.com
ContextSecond-trimester prenatal ultrasound is widely used in an attempt to detect Down
syndrome in fetuses, but the accuracy of this method is unknown. ObjectiveTo determine the
accuracy of second-trimester ultrasound in detecting Down syndrome in fetuses. Data
SourcesEnglish-language articles published between 1980 and February 1999 identified
through MEDLINE and manual searches. Study SelectionStudies were included if they
recorded second-trimester findings of ultrasonographic markers, chromosomal …
syndrome in fetuses, but the accuracy of this method is unknown. ObjectiveTo determine the
accuracy of second-trimester ultrasound in detecting Down syndrome in fetuses. Data
SourcesEnglish-language articles published between 1980 and February 1999 identified
through MEDLINE and manual searches. Study SelectionStudies were included if they
recorded second-trimester findings of ultrasonographic markers, chromosomal …
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