The serine/threonine kinase Unc-51-like kinase-1 (Ulk1) is thought to be essential for
induction of autophagy, an intracellular bulk degradation process that is activated by various
stresses. Although several proteins have been suggested as Ulk1 substrates during
autophagic process, it still remains largely unknown about Ulk1's physiological substrates.
Here, by performing in vitro and in vivo phosphorylation assay, we report that the co-
chaperone cell division cycle protein 37 (Cdc37) is a Ulk1 substrate. Ulk1-mediated …