Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment
BACKGROUND: The short (S) allele of the serotonin transporter gene-linked polymorphic
region (5HTTLPR) has been associated with poorer antidepressant response in major
depressive disorder (MDD) and with antidepressant-induced mania. This study investigated
a possible association with treatment-emergent insomnia or agitation. METHODS: Thirty-six
outpatients with MDD were genotyped at 5HTTLPR and treated with open-label fluoxetine
up to 60 mg/day. Treatment-emergent adverse effects were assessed at each study visit …
region (5HTTLPR) has been associated with poorer antidepressant response in major
depressive disorder (MDD) and with antidepressant-induced mania. This study investigated
a possible association with treatment-emergent insomnia or agitation. METHODS: Thirty-six
outpatients with MDD were genotyped at 5HTTLPR and treated with open-label fluoxetine
up to 60 mg/day. Treatment-emergent adverse effects were assessed at each study visit …
以上显示的是最相近的搜索结果。 查看全部搜索结果