Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans

KS Lee, S Iwanir, RB Kopito, M Scholz… - Nature …, 2017 - nature.com
Animals integrate physiological and environmental signals to modulate their food uptake.
The nematode C. elegans, whose food uptake consists of pumping bacteria from the
environment into the gut, provides excellent opportunities for discovering principles of
conserved regulatory mechanisms. Here we show that worms implement a graded feeding
response to the concentration of environmental bacteria by modulating a commitment to
bursts of fast pumping. Using long-term, high-resolution, longitudinal recordings of feeding …

Serotonin-dependent kinetics of feeding bursts underlie a graded response to food availability in C. elegans.

LKS Lee KyungSuk, S Iwanir, RB Kopito, M Scholz… - 2017 - cabidigitallibrary.org
Animals integrate physiological and environmental signals to modulate their food uptake.
The nematode C. elegans, whose food uptake consists of pumping bacteria from the
environment into the gut, provides excellent opportunities for discovering principles of
conserved regulatory mechanisms. Here we show that worms implement a graded feeding
response to the concentration of environmental bacteria by modulating a commitment to
bursts of fast pumping. Using long-term, high-resolution, longitudinal recordings of feeding …
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