[HTML][HTML] Serum angiopoietin-2 and soluble VEGF receptor 2 are surrogate markers for plasma leakage in patients with acute dengue virus infection

CAM van de Weg, CS Pannuti, HJ van den Ham… - Journal of Clinical …, 2014 - Elsevier
Background Endothelial cell dysfunction is believed to play an important role in the
pathogenesis of plasma leakage in patients with acute dengue virus (DENV) infection.
Several factors, produced by activated endothelial cells, have been associated with plasma
leakage or severe disease in patients with infectious diseases. Objectives The aim of this
study was to investigate which of these markers could serve as a surrogate marker for the
occurrence of plasma leakage in patients with acute DENV infection. Study design A case …
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